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Alnylam proceeds to sign up patients in its Phase II trial with ALN-TTR02 for the treating ATTR. That is an open-label, multi-center, multi-dose, dose-escalation trial made to enroll approximately 20 ATTR patients. Subjects are being enrolled into cohorts of raising doses and are receiving ALN-TTR02 once every four weeks for two cycles. The principal objectives of the analysis are to evaluate the security and tolerability of multiple doses of ALN-TTR02 and to measure clinical activity based on serial measurement of circulating serum TTR amounts. Alnylam expects to complete this trial in mid-2013. Presented Pre-scientific Data with ALN-TTRsc, a Subcutaneously Delivered RNAi Therapeutic for the treating ATTR.

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